Tag: tacrolimus level spikes

Azoles and Tacrolimus: How Antifungals Cause Dangerous Drug Level Spikes and Kidney Damage

Azoles and Tacrolimus: How Antifungals Cause Dangerous Drug Level Spikes and Kidney Damage

Azoles like voriconazole and posaconazole can spike tacrolimus levels by up to 10x, causing severe kidney damage in transplant patients. Learn how this dangerous interaction works, which antifungals are safest, and what protocols prevent toxicity.

Read More